For the past 13 years, I have used mostly transdermal creams in my Bio-Identical Hormone practice, & I find them to be the safest way to take your hormones. I have the patient apply a ¼ tsp of cream to their labial skin for best absorption. This avoids any issues with absorption fatigue, which can occur on other areas of the body.

There are several studies, particularly focusing on blood clots, heart attack and stroke, that demonstrate the very real difference between the risks posed by oral estrogen and the safety of transdermal estrogen.

 Oral estradiol can:

  • increase blood pressure
  • increase triglycerides
  • increase estrone
  • cause gallstones
  • elevate liver enzymes
  • increase SHBG (decrease testosterone)
  • interrupt tryptophan metabolism and consequently serotonin metabolism
  • lower growth hormone
  • increase clotting
  • increase CRP (inflammation)
  • increase carbohydrate cravings

Since taking over a practice where most patients are using sublingual troches, I am seeing troubling indications on the labwork, like elevated estrone & CRP, that troches are working more like an oral form of estrogen. I am committed to giving my patients the highest amount of benefit with the smallest amount of risk. If you are on a troche or other oral form of estrogen, please contact my office & we’ll discuss whether changing your troche to a transdermal form of estrogen is right for you.

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